Protein Details: Glutamate receptor 3.5

Protein ID

ICDB_Pro_1640

Protein Name

Glutamate receptor 3.5

Gene Name

GLR3.5; GLR6; At2g32390; T32F6.9

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

953 amino acids

AlphaFoldDB

AF-Q9SW97-F1-model_v4.pdb

Function

Glutamate-gated receptor that probably acts as a non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.

Sequence

MGFFVMIRDVSMGFMLLCISALWVLPIQGAGRESFSRNSSSSSLPSSVNVGALFTYDSFIGRAAKLAFVAAIEDINADQSILRGTKLNIVFQDTNCSGFVGTMGALQLMENKVVAAIGPQSSGIGHIISHVANELHVPFLSFAATDPTLSSLQYPYFLRTTQNDYFQMNAITDFVSYFRWREVVAIFVDDEYGRNGISVLGDALAKKRAKISYKAAFPPGADNSSISDLLASVNLMESRIFVVHVNPDSGLNIFSVAKSLGMMGSGYVWITTDWLLTALDSMEPLDPRALDLLQGVVAFRHYTPESDNKRQFKGRWKNLRFKESLKSDDGFNSYALYAYDSVWLVARALDVFFSQGNTVTFSNDPSLRNTNDSGIKLSKLHIFNEGERFLQVILEMNYTGLTGQIEFNSEKNRINPAYDILNIKSTGPLRVGYWSNHTGFSVAPPETLYSKPSNTSAKDQRLNEIIWPGEVIKPPRGWVFPENGKPLKIGVPNRVSYKNYASKDKNPLGVKGFCIDIFEAAIQLLPYPVPRTYILYGDGKKNPSYDNLISEVAANIFDVAVGDVTIITNRTKFVDFTQPFIESGLVVVAPVKGAKSSPWSFLKPFTIEMWAVTGALFLFVGAVIWILEHRFNEEFRGPPRRQIITVFWFSFSTMFFSHRENTVSTLGRFVLLVWLFVVLIINSSYTASLTSILTVQQLTSRIEGMDTLIASNEPIGVQDGTFAWKFLVNELNIAPSRIIPLKDEEEYLSALQRGPRGGGVAAIVDELPYIKALLSNSNCKFRTVGQEFTRTGWGFAFQRDSPLAVDMSTAILQLAEEGKLEKIRKKWLTYDHECTMQISDTENYQISVQSFWGLFLICGVVWFIALTLFCWKVFWQYQRLRPEESDEVQARSEEAGSSRGKSLRAVSFKDLIKVVDKREAEIKEMLKEKSSKKLKDGQSSAENSQSKDHETPQ

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed predominantly in roots. Also detected in shoots.

DOI ID

10.1126/science.292.5521.1486b; 10.1038/45471; 10.1111/tpj.13415; 10.1093/oxfordjournals.molbev.a004165

RefSeq

NP_001324013.1 [Q9SW97-1]; NP_565743.1